Description

How Supplied:

Each 5 ml syrup contains 100 mg Guaifenesin. 60 ml syrup in a bottle.

Category

Expectorant

Mechanism of Action

Guaifenesin is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi.

Pharmacokinetics

Absorption

Readily absorbed from gastrointestinal tract

Distribution

No information is available on the distribution of guaifenesin in humans.

Elimination

Renal, as inactive metabolites

Dosage and Administration

Usual adult and adolescent dose:

200 to 400 mg every four hours. Not to exceed 2400 mg a day.

Usual pediatric dose:

Children 6 months to 2 years of age

25 to 50 mg every four hours. Not to exceed 300 mg a day.

Children 2 to 6 years of age

50 to 100 mg every four hours. Not to exceed 600 mg a day.

Children 6 to 12 years of age

100 to 200 mg every four hours. Not to exceed 1200 mg a day.

Pregnancy and breast feeding

FDA pregnancy: category C. It is not known whether guaifenesin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether guaifenesin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Side Effects:

Less common or rare:

Diarrhea- dizziness- headache- hives- nausea or vomiting- skin rash- stomach pain.

Precautions

• Use in children: for self-medication, caution if cough is persistent or occurs with excessive phlegm; not administering to children younger than 2 years of age unless directed by a physician.
• Checking with physician if cough persists after medication has been used for 7 days or if fever, skin rash, continuing headache, or sore throat is present with cough.

Drug interactions

Guaifenesin should not be combined with cough suppressants in the treatment of cough since the combination is illogical and patients may be exposed to unnecessary adverse effects.

Storage

Store below 30˚c. Store in a tight container. Protect from freezing. Keep out of reach of children.